Her team is also working on a menopause-focused intervention designed to support brain health while addressing concerns around hormone therapy. Ultimately, their goal for Alzheimer’s is two pronged – the first is to reduce the risk, the second, is to develop a menopausal intervention for hot flashes called phytoserm, phyto for plant, and serm for selective estrogen receptor modulator. “About 80% of women elect not to receive menopausal hormone therapy for the fear of breast cancer, and our we listened to women. We were telling them how great estrogen is, and it is, right? But we listened to women decades ago, and realized that if we wanted to reduce women’s risk of developing Alzheimer’s disease and sustain their brain health, we had to listen and address their concerns about breast health,” Brinton outlined, concluding, “So, we developed a formulation of natural plant-based molecules that promote brain health and sustain breast health by selectively targeting a type of estrogen receptor, estrogen receptor beta, that works like an estrogen in the brain and not in the breast.”
