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Papaya leaf extract is perhaps the most popular home remedy for dengue. While Caripill, a standardized papaya leaf extract approved by the Central Drugs Standard Control Organization (CDSCO), is available as supportive therapy, doctors stress that it is not a cure for dengue. Homemade papaya leaf juice is very different. The concentration of active compounds varies widely, and improper preparation may introduce contaminants or cause stomach irritation.